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The Pyo 2007 study (PMID 17703734) reported that AHK-Cu raised VEGF production in the treated cells

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[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Dijk W, Mattijssen F, de la Rosa Rodriguez M, Loza Valdes A, Loft A, Mandrup S, et al

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Interestingly, research has shown that even in animals lacking beta-3 adrenergic receptors, acute AOD-9604 administration still increased energy expenditure and fat oxidation, suggesting additional metabolic pathways may be involved beyond the primary beta-3 receptor mechanism

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