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As predicted by preclinical studies with EPO (5) and ARA 290 (10,38), subjects receiving ARA 290 exhibited significant improvement in glucose control as shown by changes in Hb A 1c concentration

& Lim, C

FIGURE 4 2.3.1 GSH metabolism and ferroptosis In breast cancer, elevated GSH levels are frequently observed, especially in TNBC, potentially attributed to estrogen-mediated downregulation of transferrin receptor expression (Ge A

& Miller, O