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Small-molecule inhibitor characterisation

The initial inflammatory modulation begins within the first one to two weeks, but the functional changes, including improved flexibility, reduced global stiffness, and better circulation, accumulate over four to eight weeks as the compounds systemic effects build through repeated dosing

It has been widely studied for its role in promoting wound healing, improving skin elasticity, and reducing inflammation

That takes randomized, controlled clinical trials

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Increased atherosclerotic plaque in AOC3 knock-out in ApoE(-/-) mice and characterization of AOC3 in atherosclerotic human coronary arteries