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The activated ErbB2 (also known as neu or HER2) is a major driver of cancer [102]

Chronic hyperglycemia results in the suppressed activity of mTOR associated with AMP-activated protein kinase-induced increase in ROS formation and enhanced expression of thioredoxin interacting protein (TXNIP) a potential sensor of glucose and oxidative stress (Akpoveso et al

References: [1] JEFFREY D POLLARD