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It is activated in more than 50% of BCs and is associated with decreased overall survival [95, 96]

(2005) Irreversible inhibition of trypanothione reductase by unsaturated Mannich bases: A divinylketone as key intermediate

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What KPV brings to Klow: NF-B inhibition: KPV blocks nuclear factor kappa-B, the "master switch" of the inflammatory response

doi: 10.1016/j.cell.2020.07.020 14