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In humans, CYP3A is readily induced by xenobiotics, is activated by CYP3A inducers, and leads to activation of PXR (Kliewer 2003

"Methyl donor supplementation reduces phosphoTau, Fyn and demethylated protein phosphatase 2A levels and mitigates learning and motor deficits in a mouse model of tauopathy"

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The nitroxide Tempo inhibits hydroxyl radical production from the Fenton-like reaction of iron(II)-citrate with hydrogen peroxide

Glenn Laboratories for the Biological Mechanisms of Aging at Harvard, of which Sinclair became the founding director

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