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Central to this approach are dose modification protocols guided by the Common Terminology Criteria for Adverse Events (CTCAE), which provide standardized thresholds for adjusting or withholding treatment based on toxicity grade

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Funding This work was supported by grants from the National Natural Science Foundation of China (NSFC Numbers 81672800, 81603009, 81673020, 81802632, and 82173830), Natural Science Foundation of Shaanxi (2020JQ-445), and the Key Research and Development Program of Shaanxi Province (2021SF-207, 2021SF-223, and 2022ZDLSF05-19)

Reduces Melanin Production Glutathione blocks the enzyme tyrosinase, which is responsible for melanin synthesis

ANTIOXIDANT SUPPORT: As a powerful antioxidant, L-Glutathione protects cells from oxidative stress and free radical damage caused by environmental factors like pollution, UV rays, and toxins

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