Shea 2008
In general, older adults often need lower doses of CNS-active compounds due to changes in metabolism, body composition, and tissue sensitivity
Furthermore, MB has been shown to stimulate cytochrome c oxidase activity, supporting efficient mitochondrial respiration
The connection between MET and ASD is supported by the fact that MET is expressed in brain areas involved in higher levels of cognition, executive functions, and language skills (Judson et al., 2011
Bacterial infections are among the most life-threatening healthcare challenges, accounting for approximately 13.6% of global mortality and affecting 1 in 8 individuals worldwide ( Beyond their pathogenic roles, bacteria are integral to human health, especially in the gut, contributing to immune modulation and digestion ( The human microbiome, especially the gut microbiota, comprises numerous symbiotic bacterial species (e.g., Lactobacillus , Bacillus , Clostridium , Enterococcus , and Ruminococcus ) that collectively represent approximately 90% of the gut flora ( While antibiotics effectively eliminate harmful pathogens, their indiscriminate targeting also affects beneficial bacteria, reducing microbial diversity and increasing the likelihood of antibiotic resistance ( The decreasing efficacy of antibiotics and the limited availability of alternative treatments underscore the urgent need for new classes of antibacterial therapeutics
Brand, Ph.D
