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Hormone replacement therapy (HRT) and other medications such as testosterone are often recommended to help alleviate these bothersome symptoms

Psychiatry Res 250: 3034, 2017

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More recent work linked long-term NS work ( 10 years) to significant hypomethylation in 85 CpG sites, including loci in ZFHX3, a gene involved in circadian rhythm regulation and tumor suppression, and ATXN7, associated with transcriptional control and cancer susceptibility 231

The effects of SF to ameliorate these two major sources of indoor and environmental air pollution have been evaluated in clinical studies using a variety of biomarkers [93,94,98]