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Pathak treated an atherosclerotic mouse model with the mechanism-based choline TMA lyase inhibitor IMC, a drug similar to DMB, which can prevent the diet-driven accumulation of cholesterol and change the expression of hepatic genes essential for bile acid feedback regulation ( Ihubacter massiliensis and/or Emergencia timonensis in the human gut can synergistically contribute to diagnosing high-TMAO producers, with 43% sensitivity and 97% specificity (95)

Selman, C., Lingard, S., Gems, D., Partridge, L

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Blood glucose level was monitored using the glucose oxidase method throughout the duration of the study

To ensure a balance between groups, block randomization with a block size of 4 was applied

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