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IGF-1 is also produced locally in all bodily tissues [92]

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[9] Patients should be advised to contact their healthcare provider if they experience any severe or persistent side effects, such as difficulty breathing, chest tightness, severe rash, or dizziness

Results can vary depending on individual B12 levels and overall health

[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations

Pregnant or breastfeeding women who suspect B12 deficiency should have their levels tested by their prenatal care provider, who can recommend the appropriate supplementation route and dosage