This matters more than people expect
McNamara RK, Jandacek R, Rider T, et al
All of the velocities are given by Michaelis-Menten kinetics, with the K m values taken from the literature, and where available, from human data
Delay of UV induced eye lens protein damage in guinea pigs by dietary ascorbate

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A critical review of the literature suggested that paracetamol clearance is lower in neonates but that neonates and children are capable of NAPQI formation, particularly following multiple sequential overdoses , and that toxicity can occur