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It usually affects one joint at a time (often the big toe joint)

Rodent studies show that it modulates dopamine receptor sensitivity and can attenuate or potentiate the behavioral effects of dopaminergic drugs, including haloperidol and amphetamine

Nature genetics

While these researchers' work appears rigorous from a technical standpoint, the lack of independent replication from other laboratories globally is a significant concern in scientific research

Machine Learning Differentiates Enzymatic and Non-Enzymatic Metals in Proteins

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