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In double-blind, placebo-controlled trials, daily application of GHK-Cu cream at 3% concentration for 12 weeks produced a 70% increase in skin collagen thickness as measured by ultrasound imaging, a 40% increase in skin elasticity, and visible reduction in fine lines and wrinkles

A B12 self-injection pen is available as an option for patients who prefer it over a traditional syringe

As an unapproved substance, AOD-9604 is not eligible for pharmacy compounding for human use

B12 injections deliver the vitamin directly into the bloodstream, ensuring maximum absorption and immediate effects, whereas oral supplements must pass through the digestive system, which can result in lower absorption rates and slower onset of action

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The safety argument is equally compelling