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reported a hypoxia-sensitive prodrug conjugate 5E , by the combination of anticancer drug SN38, cancer-targeting biotin, and hypoxia-sensitive self-immolative linker 4-nitrobenzyl, for the diagnosis and treatment of solid tumors 126

Dekhuijzen PN, van Beurden WJ

[ref] As wounds and damaged tissue heal, they rely on the formation of new blood vessels, which is another way that BPC-157 promotes healing.[ref] BPC-157 increases the formation of blood vessels by increasing the expression of vascular endothelial growth factor receptor 2 (VEGFR2)

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These studies found no evidence of toxicity, organ damage, or concerning changes with chronic administration