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Changes in protein consumption [69], including reducing protein levels but remaining within safe levels, may alter plasma glutathione synthesis levels contributing to a reduction in antioxidant capacity

Its effects are more gradual and cumulative, working through cellular signaling and tissue remodeling processes that unfold over hours to days

Despite studies on the effects of antioxidant therapies still being controversial and further randomized controlled trials being necessary [169], some evidence from in vitro studies and animal models [170,171] provides interesting data on their efficacy and the type of formulation to be used

doi: 10.3389/fnut.2019.00048 81 ChenACMartinAJChoyBFernndez-PeasPDalziellRAMcKenzieCAet al

Diabetologia 51 , 11531158 (2008)