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B12 is essential for the normal function of immune cells, and deficiency has been associated with impaired immune responses

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ADP-ribosylation of RNA Beyond decorating RNA as a nucleotide analog, NAD + also provides the ADPR groups for the reversible mono-ADP-ribosylation of RNA phosphorylated ends

10.1212/01.wnl.0000256715.13907.d3 Neurology 129 LoquetA.BardiauxB.GardiennetC.BlanchetC.BaldusM.NilgesM.et al (2008)

Its ability to protect and regenerate the mucosal lining, reduce inflammation, and improve local blood flow makes it relevant across a spectrum of digestive disorders and gut dysfunctions

Common side effects include pain or redness at the injection site, mild diarrhea, itching, and swelling