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Dexmedetomidine attenuates myocardial ischemia/reperfusion-induced ferroptosis via AMPK/GSK-3/Nrf2 axis

Pharmacokinetic studies in rats demonstrated an oral bioavailability of 38.4%, with a mean Cmax of 2,252 ng/mL and terminal elimination half-lives of 3.80 1.10 hours (IV) and 6.90 1.20 hours (oral) (Awosemo et al., 2021)

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Blood selenium and glutathione peroxidases in miscarriage