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In a randomized controlled clinical trial, leg ulcers treated with EpiFix in addition to multilayer compression therapy had an average reduction in size over four weeks of 48.1% compared with 19% for those treated with compression only (Serena 2014)

R&D pipeline

More importantly, they showed reduced markers of apoptosis

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However, the comprehensive benefits often justify the cost for those seeking a more holistic approach to NAD therapy