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The human gut microbiome plays a pivotal role in nutrient metabolism, immune system development, and drug metabolism

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Abstract Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural abnormalities or impaired excretory renal function suggestive of a loss of functional nephrons

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however, at least in retinal pigment epithelial cells, A-mediated oxidative stress has also been linked to inflammasome assembly, with the participation of mitochondria [16]

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