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The trial concluded that AOD-9604 did not induce significant weight loss, leading to a halt in the development of the drug as a weight-loss solution

Interestingly, RSL3-induced ferroptosis could be inhibited by higher expression levels of mitochondrial ferritin under hypoxic conditions [60]

It also plays a vital role in the regeneration of other antioxidants such as vitamins C and E, enhancing the body's total antioxidant capacity

Most patients present with a subset of these rather than the complete picture

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