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London: IntechOpen (2022) 23

Regulatory approval (if granted) would provide quality assurance and prescriber guidance that research-grade use cannot

Clinically Proven: Tested in human trials to visibly enhance skin tone and radiance for a revitalized appearance

Biopsy can be helpful even in early stages if the diagnosis is uncertain, but it is more definitive in later stages with the hallmark manifestations of full-thickness necrosis and subepidermal detachment