Research evidence for combination effects While direct head-to-head comparison studies of the combination versus individual peptides remain limited, the mechanistic evidence strongly supports synergistic interactions
There isnt a one-size-fits-all schedule for B12 shots
For those with a B12 deficiency and an MTHFR mutation, one major advantage of B12 injections is that they are readily absorbed in the body and do not have to be taken as often as oral tablets
B12 supplements are readily available in oral tablets, oral solutions, mouth sprays, and under-the-tongue tablets, and they range in dosage amounts from 5 mcg to 5,000 mcg depending on the type of supplement
Natural sources of Vitamin B12 include animal products such as meat, poultry, eggs, and dairy, as well as fortified foods like cereals
Alcohol & stress: Limit alcohol (its metabolism consumes NAD+) and manage stress, since chronic stress activates PARPs that deplete NAD+ pools