This OS and the breakdown of acetaldehyde can result in the creation of DNA adducts and may be associated with epigenetic modifications of DNA, like methylation [180]
The Annals of Pharmacotherapy , 46 (2), 240247
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Cells were fixed with formaldehyde and incubated with anti-Myc antibody (Abcam, catalog number ab9106) to detect DARPin expression and -p53 antibody DO-I (Santa Cruz Biotechnology) to detect p53 expression, followed by incubation with the secondary antibodies Alexa Fluor 568 anti-rabbit (Life Technologies) and Alexa Fluor 647 anti-mouse (Life Technologies)