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Cells were blocked with 1% bovine serum albumin in PBS for 1 h and then incubated with anti-PGC-1 (1:100, ABclonal, Wuhan, China) antibody at 4 overnight

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The kidney and liver function values also showed no significant differences between the pre-dose and post-dose values in any group (Table 1)

Studies showed that people who took Wegovy lost an average of around 15% of body weight after 68 weeks of treatment