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Systemic inflammation in T2D is further exacerbated by reduced levels of bacteria with anti-inflammatory activity that stimulate IL-10 and IL-22 secretion ( Roseburia , Akkermansia , Bacteroides , Faecalibacterium ), as well as those inducing Treg cells ( Clostridium clusters IV and XIVa)

By promoting keratinocyte activity and extracellular matrix repair, GHK-Cu may help strengthen this barrier and improve resilience in damaged or sensitive skin