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However, scRNA-seq data show that a substantial fraction of -cells in humans and mice express neither GLP1R nor GIPR, or only one of them ( Glp1r:mTmG mouse models, where 78% of -cells appear GLP1R-positive, suggesting that technical limitations or post-transcriptional regulation may explain the discrepancy (Tong et al., 2025)

Lack of sleep over a long period of time drains stores, making it harder to get rid of toxins and fight off sickness

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