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18,19,20,21 Finally, IL-17 and IL-8 (CXCL8) promote inflammation, recruitment and activation of neutrophils and increased levels have been found in autoimmune diseases such as systemic lupus erythematosus, inflammatory bowel disease and psoriasis

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In pediatric population, this has generally been mitigated by enteral tube feeding, a strategy which is not typically feasible in adult and adolescent subjects especially in outpatient settings

In this respect, it is plausible that autoimmune responses, which play a role in chronic fatigue syndrome and depression [28, 119] and Long COVID [120], and pulmonary fibrosis with scarring and cardiac remodeling [71] contribute to neuropsychiatric symptoms