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10.3389/fmed.2020.629413 Front Med

Clarifying the confusion: Brightening vs

Vitamin B3 (Niacin): Vitamin B3, or Niacin, is essential for maintaining healthy skin

Through co-culture experiments with glial cells and neurons, it was found that glial cells can help neurons resist oxidative stress by secreting antioxidants or helping antioxidant precursors

Thiankhaw et al., 2022)

In PCOS, oxidative stress contributes to: Hormonal disruption Insulin resistance Inflammation Poor skin recovery Pigmentation flare-ups Glutathione helps by: Reducing free radical damage Supporting cellular repair Calming stress-driven melanin activity This is why skin issues in PCOS often improve after internal balance improves , not before