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They regulate cardiomyocyte growth, stress adaptation, signal transduction, ion channel turnover, autophagy-proteasome crosstalk, congenital heart disease mechanisms, and cardiomyopathies

New England Journal of Medicine 361, 25182528 (2009)

NRF2 SUMOylation is mediated by a sequential enzymatic process involving the SUMO-activating enzyme E1, the SUMO-conjugating enzyme E2, and the SUMO ligase E3 [128]

6 The free CD is accumulated in the mitochondria, inhibiting the respiratory chain in the complex III

Glutathione is a tripeptide, which is a small protein-like molecule made of three specific amino acids: cysteine, glycine, and glutamate