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A separate experiment elucidated that Gln supplementation increased cardiac GSH to halt myocardial injury induced by cyclophosphamide (CPA) in rats [112]

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PDI (C81H6) rabbit monoclonal antibody (Cell Signaling Technology, 3501S), 1:100

doi: 10.1158/0008-5472.CAN-08-1875 89 KimMKohYJKimKEKohBINamDHAlitaloKet al

In addition, ROS can activate the expression of the nuclear transcription factorkappa, which upregulates the expression of many genes involved in MS, such as tumor necrosis factor and nitric oxide synthase, among others, leading to mitochondrial dysfunction and energy deficits that result in mitochondrial and cellular calcium overload

[DOI] [PubMed] [Google Scholar] McFadden SL, Ding D, Burkard RF, Jiang H, Reaume AG, Flood DG, Salvi RJ