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They do not primarily serve as nutritional protein, but as signalling molecules

Importantly, the application of ferrostatin-1 successfully mitigated the ferroptosis and EMT-related dysfunctions, indicating promising pathways for therapeutic intervention ( Tumor protein p53 (TP53) , Enhancer of Zeste Homolog 2 (EZH2 ), Tissue inhibitor matrix metalloproteinase 1 (TIMP1) , Solute carrier family 3 member 2 (SLC3A2), and Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) (Zeng et al., 2025)

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This is real and reproducible at the molecular level

In tissue repair models, angiogenesis is important because damaged tissue needs a functional vascular response for oxygen delivery, nutrient movement and repair signalling

Nat Rev Neurosci 11(2):114126