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At body temperature (37 degrees Celsius), degradation is roughly eight times faster

NYG2024146, NYG2024141)

Superoxide dismutase catalyzes the conversion of superoxide radicals into hydrogen peroxide, which is then broken down by catalase and GPx into water and oxygen, thereby preventing the accumulation of toxic byproducts and preserving the structural and functional integrity of sperm cells

Theranostics 15 , 30553075 (2025)

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Furthermore, based on mechanistic insights, the review explores targeted gut microbiota interventions, systematically evaluating clinical evidence for dietary modifications, probiotic/prebiotic supplementation and fecal microbiota transplantation