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The most important principal to remember is that medical management is effective but that symptoms tend to recur rapidly after therapy is stopped

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These links reflect shared immunogenetic factors, including IL-18, IFN-, CTLA-4, HLA-DQ8, HLA-DQ2, HLA-B8, and HLA-DR3, many of which are integral to antigen presentation within the major histocompatibility complex (MHC)

2020;881 doi: 10.1016/j.ejphar.2020.173210

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