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Given that GPX4 is an essential selenoprotein whose activity is wholly dependent on selenium bioavailability, these mutations result in a progressive decline in GPX4 expression

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Consult en mai 2020. Thakker D, Raval A, Patel I, Walia R

Oncogene 30 , 18551867 (2011)

They survive low oxygen and high inflammation the exact conditions inside a worn-out joint or damaged disc