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2008 Oct;42(10):1481-5

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99,219 In excitatory neurons, CaMKII functions as a shuttle molecule to collect Ca 2+ /Calmodulin from the cytoplasm and transport it to the nucleus, where Ca 2+ /Calmodulin release activates CaMKK and its substrate CaMKIV to further phosphorylate CREB, thereby participating in the regulation of transcription and translation

Physical therapy strengthens muscles but can't repair years of microscopic damage

Enzyme kinetic studies in endothelial cell models demonstrate increased eNOS (endothelial nitric oxide synthase) activity following compound application