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RG contributed during different stages of manuscript preparation starting from drawing the review outline to checking drafts at every stage for technical corrections and improving overall language for finalizing the manuscript

After six months, the goal shifts from repair to optimization. Long-term users generally report a higher baseline of health

Genes with very little variability were non- specifically filtered using a standard deviation threshold of 50% to simplify the graph

Semaglutide 2.4 mg once weekly, a subcutaneously administered GLP-1 RA approved for obesity treatment in 2021, results in 1517% mean weight loss (WL) with evidence of cardioprotection