Abstractive Summary The copper peptides backlash currently spreading across skincare communities reflects a wider pattern in modern routines: potent active ingredients are increasingly available at consumer level without the layering knowledge that makes them safe
Fat Loss and Improved Metabolism Promotes lipolysis (fat breakdown)
Copper-Binding Properties Both peptides demonstrate strong copper-binding capabilities, which is essential for their biological activities
An increased Ca/Mg might also impact this, as Mg ++ is required to synthesize cAMP and cGMP that mediate the release of renin from the juxtaglomerular apparatus (Persson, 2003)
The catch: at 340.4 daltons, GHK-Cu sits above the 500-dalton passive penetration ceiling of intact human skin
Increasing GSH through synthesis would also seem to be useful therapeutically but as oxidants and most electrophiles would not seem appropriate, natural compounds such as curcumin, a principal ingredient of curry powder (Dickinson et al., 2003), and sulforaphane, a potent Phase II gene-inducing compound in broccoli, (Brooks et al., 2001) have been proposed but none of these natural has actually become a major therapeutic agent
