3.6.3 Mechanisms linking gut dysbiosis to PSCI 3.6.3.1 Neuroinflammation Gut dysbiosis and increased intestinal permeability following ischemic stroke (IS) have been linked to systemic endotoxemia and altered microbial metabolite signaling, potentially exacerbating neuroinflammation and injury (Zhang W
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Proc Natl Acad Sci USA 104:40774082 Zhang WJ, Bird KE, McMillen TS, LeBoeuf RC, Hagen TM, Frei B (2008) Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice
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