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Ethacraplatin Ethacraplatin is a bifunctional drug developed to overcome GST mediated cisplatin resistance 92

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Natural products also demonstrate promise: the fungal-derived meroterpenoid granulathiazole A (GA) activates Nrf2/HO-1 signaling, inhibits ferroptosis via SLC7A11/GPX4/FSP1 upregulation and ACSL4 downregulation, and reduces -syn accumulation across cellular and zebrafish models (Li et al., 2024a)

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Nat Commun 8(1):49