Furthermore, chow-fed Gpr146 / mice displayed significantly increased lean mass without changes in fat mass (Supplementary Fig
The increase in hTERT seen was lower than what was obtained in the cancer cell lines, suggesting that normal cells have a more robust pathway for telomerase regulation which needs to be overcome for full expression of hTERT
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[] It has been found to impede cell cycle progression by arresting the G0/G1 phase, thereby reducing cellular proliferation in PCa
