The pleiotropic properties of metformin suggest that the drug acts on multiple tissues through various underlying mechanisms rather than on a single organ via a unifying mode of action
doi: 10.3389/fonc.2022.913669 Received 06 April 2022 Accepted 11 May 2022 Published 03 June 2022 Volume 12 - 2022 Edited by Jianming Li, Soochow University, China Reviewed by Yang Li, Shanghai University of Traditional Chinese Medicine, China
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Lee S, Olsen T, Vinknes KJ, Refsum H, Gulseth HL, et al
Responsible for keeping our cells free from toxin Fucoidan - Protect against cell damage
As a transcription factor, NRF2 binds to specific enhancer sequences termed antioxidant response elements (AREs) to promote transcription of numerous detoxification enzymes and antioxidant genes [25]