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Fas-stimulated generation of reactive oxygen species or exogenous oxidative stress sensitize cells to Fas-mediated apoptosis

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doi:10.1007/s00441-019-03016-8 Mayfield CK, Bolia IK, Feingold CL, et al

These findings provide evidence for the importance of the GSH system in anti-ferroptosis

Under physiological conditions, ROS are generated in the heart mainly from the mitochondrial electron transport chain, nitric oxide synthases (NOS), NADPH oxidases (NOX), and xanthine oxidase (XO) in small quantities [7, 8]

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