Lyophilised AOD-9604 should be stored at 20 C protected from light, stability 2 to 3 years
Injection site reactions commonly cause swelling, redness, and pain at the injection site, appearing within 48 hours after vaccination and typically lasting 1-2 days
Hormonal factors can blunt the response
Quickly insert the needle into the muscle
By means of the enzyme lysine-specific demethylase (LSD-1), it ensures the demethylation of histones, whereby some genes are increasingly expressed
This includes confirmed low serum vitamin B12 levels, pernicious anaemia, malabsorption states such as coeliac disease, inflammatory bowel disease, or post-gastric or bariatric surgery, unexplained anaemia, neuropathy or neurological symptoms consistent with vitamin B12 deficiency, a long-term vegan diet with symptoms or low levels, or failure of oral vitamin B12 supplementation