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Nuclear factor erythroid 2-related factor 2 plays a fundamental role in the response to oxidative stress and xenobiotic metabolism and detoxification, and the Nrf2 signaling pathway is intimately associated with development of atherosclerosis

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Frontiers in Nutrition, 6(6), 1-11

Sarbaziha notes that levels peak in young adulthood before declining, and she outlines how the compound modulates gene expression tied to repair processes in addition to exerting acute effects on oxidative stress

NCU04343 was thus determined to be the first biosynthetic gene in EGT biosynthesis and was renamed egt-1