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DiNardo, C, Verma, D, Baran, N, Bhagat, TD, Skwarska, A, Lodi, A, Saxena, K, Cai, T, Su, X, Guerra, VA, Poigaialwar, G, Kuruvilla, VM, Konoplev, S, Gordon-Mitchell, S, Pradhan, K, Alluri, S, Hackman, GL, Chaudhry, S, Collins, M, Sweeney, SR, Busquets, J, Rathore, AS, Deng, Q, Green, M, Grant, S, Demo, SD, Choudhary, GS, Sahu, S, Agarwal, B, Spodek, M, Thiruthuvanathan, V, Will, B, Steidl, U, Tippett, G, Burger, JA, Borthakur, G , Jabbour, EJ, Pemmaraju, N, Kadia, TM, Kornblau, SM, Daver, N, Naqvi, K, Short, NJ, Garcia-Manero, G, Tiziani, S, Verma, A, Konopleva, M
10.1152/ajpcell.00329.2011 135 MuzaaleA.KhanA.GlassockR
half life 1.5-3 hours excreted by the kidney (no metabolism) Side Effects: Rare : dose-related incidence of lactic acidosis GI side effects (diarrhea, nausea, vomiting, abdominal bloating, gas, reduced appetite) (~20% of patients develop dose-related GI side effects) Vitamin B12 deficiency
[11] Babault N, Pazis C, Deley G, et al
The distance that each mouse travelled and the proportion of time spent exploring the central 45 cm of the field were determined
In cell culture studies, BPC-157 has been shown to increase tendon fibroblast migration and survival under oxidative stress, and to enhance fibroblast outgrowth from tendon explants effects relevant to connective tissue repair
