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Improper handling degrades them, potentially creating breakdown products that differ in effect from the intact peptide

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This feature was exploited for selective and sensitive quantification of creatinine (CRN) which is an important diagnostic parameter

"The procognitive and synaptogenic effects of angiotensin IV-derived peptides are dependent on activation of the hepatocyte growth factor/c-met system." Journal of Pharmacology and Experimental Therapeutics

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