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Because vitamin (especially folate) supplementation can efficiently reduce plasma homocysteine levels, further prospective cohort studies and ongoing, randomized, placebo-controlled trials will determine the efficiency of folate supplementation, possibly in combination with vitamins B 12 and B 6 , in the prevention and correction of vascular disorders related to moderate hyperhomocysteinemia

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This strategy enhances protective immunity against challenges with MC38 tumor cells, resulting in decreased tumor growth and increased CD8 + T cells in the tumor