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It creates a stable target for the needle, and it lifts the subcutaneous fat layer away from the muscle, dramatically reducing the chance of an intramuscular injection

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On the other hand, we found that, whereas the presence of cortistatin induced a less inflammatory peripheral nerve microenvironment, it increased or maintained the levels of two neurotrophins, such as GDNF and BDNF, which promote growth and regeneration of damaged axons [67,68]