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5 (5), 17371742 (2014) L

Unfortunately, pollution, poor diet, age, infections, medication, and stress significantly deplete its levels

Glutathione also helps the body detoxify by eliminating pollutants and toxins through the liver, whether they come from our environment or our diet

The active site of the other three GPXs is cysteine [64]

It is also a potent detoxifier and a very effective protector of our immune system, thus keeping our skin and organs in perfect condition

While a substitution with the polar serine at position 13 retained wild-type dehydratase activity, presumably due to the alcohols ability to assume cysteines function in stabilizing deprotonated GS , the only other Pt GSTF8 variants to keep analbeit reducedflavan-3,3,4-triol ( 4 ) dehydration activity contained a glycine, alanine or asparagine mutation (Fig